文献简介

出版社:Journal of Pain & Palliative Care Pharmacotherapy

作  者:Liam Conroy

编  号:10.3109/15360288.2014.1003679

关键字:disk | protrusion | pain | sciatica | opioids | steroids

年  份:2015   点击量:1025

文献摘要 全文翻译

Lumbar intervertebral disk protrusion can cause excruciating pain in severe cases, which can be exacerbated by activity such as sitting down and straining at stool. Acute sciatica due to disk rupture will improve within 1 to 3 months. The efficacy of drugs used for the management of sciatica in primary care is unclear. Severe cases can require opioid analgesia, however people taking opioids for pain relief frequently present with opioid-induced bowel dysfunction. The use of transforaminal steroid injections is a controversial issue and repeat steroid injections should be considered in light of the risk-benefit profile of the individual patient.

一些严重病例中,腰椎间盘突出症会引起剧烈疼痛,这种疼痛可因活动而加剧,如落坐和用力排便。椎间盘破裂引起的急性坐骨神经痛在1-3个月内会有所改善。坐骨神经痛初级治疗的药物疗效尚不明确。严重的病例需服用阿片类药物镇痛,然而患者服用阿片类药物缓解疼痛的同时常伴随阿片类药物诱导的肠功能紊乱。椎间孔类固醇注射治疗仍有争议,个别患者应当在权衡风险-利益后才考虑再次接受类固醇注射。